The double-blind, placebo-controlled clinical study, which was conducted at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, involved 55 middle-aged patients diagnosed with metabolic syndrome. All the participants underwent screening at the beginning of the study to measure the total coronary plaque volume as well as dense calcium, non-calcified plaque, and low-attenuation plaque. The screening was conducted using Cardiac Computed Tomography Angiography (CCTA), a revolutionary noninvasive imaging technology that accurately measures calcium deposits and plaque buildup in the arteries.
Following evaluation, the participants were given either a placebo or a dose of 2,400mg Aged Garlic Extract every day. A follow up screening was conducted a year after initial screening to assess any potential changes. The UCLA researchers, led by Matthew Budoff, MD, found that the patients taking Aged Garlic Extract had slowed total plaque by 80%, reduced soft plaque, and demonstrated regression (less plaque on follow-up) for low-attenuation plaque, the most vulnerable component of atherosclerosis. This is the first time that a natural supplement has been shown to control or reverse heart disease.
The chemical conversion brought about the aging process results in eliminating the pungent odor of the garlic and providing AGE with its various health–promoting benefits, without the unpleasant side effects (i.e., offensive odor and potential indigestion) of fresh raw garlic. AGE also contains small amounts of oil-soluble organosulfur compounds, along with flavanoids and selenium, among other health-giving nutrients.